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Clinical Research and Trials

Clinical trials play a crucial role in advancing cardiovascular care, helping researchers develop new medicines, medical devices, and treatment approaches that improve the lives of people living with heart disease.

Patient involvement is essential to ensuring research reflects real-world experiences and addresses the needs and priorities of the people it is designed to help.

What is a clinical trial?

A clinical trial is a type of research study involving people that aims to evaluate the safety and effectiveness of a treatment, medical device, procedure, lifestyle intervention, or model of care.

Clinical research helps improve our understanding of heart disease and supports the development of new ways to prevent, diagnose, treat, and manage cardiovascular conditions.

It’s important to remember that not all clinical trials involve testing new medicines. Research studies may also explore medical devices, exercise programs, rehabilitation approaches, digital health tools, surveys, and other ways to improve health outcomes and quality of life.

Why are clinical trials important?

Clinical trials help:

  • Improve the prevention, diagnosis, and treatment of heart disease
  • Develop new medicines, devices, and therapies
  • Improve quality of life and patient outcomes
  • Ensure healthcare decisions are based on evidence
  • Advance innovation in cardiovascular care
  • Give patients a voice in shaping future healthcare and research

Understanding Clinical Trial Phases

Clinical trials are conducted in phases, with each phase designed to answer specific questions about a treatment’s safety and effectiveness.

Phase 1 Tests a new treatment in a small number of people to assess safety and determine the appropriate dosage
Phase 2 Involves a larger group of participants to evaluate how well the treatment works and monitor side effects
Phase 3 Compares the new treatment against existing standard treatments in larger groups of people
Phase 4 Occurs after approval and monitors the long-term safety and effectiveness of the treatment in the broader community

Clinical trials are conducted under strict ethical and regulatory requirements and are carefully monitored to help protect the rights, safety, and well-being of participants.

Find a Clinical Trial

Ready to explore clinical research opportunities?

As part of our affiliation with Global Heart Hub, we’re proud to share a user-friendly Clinical Trials Portal designed to help people living with cardiovascular disease learn more about clinical research and identify potential opportunities to participate in clinical trials.

Use the Global Heart Hub Clinical Trials Portal to search for cardiovascular clinical trials that may be relevant to your condition, interests, or location. To find studies available locally, simply select Australia or New Zealand when searching.

Who can participate?

Every clinical trial has its own eligibility criteria. Some studies are looking for people living with a particular condition, while others may seek healthy volunteers.

Participation is always voluntary, and participants are provided with detailed information about the study, including its purpose, potential risks, and possible benefits, before deciding whether to take part.

What does participation involve?

Every study is different. Depending on the trial, participants may:

  • Receive a new treatment or medical device
  • Continue with their usual care while providing feedback
  • Complete surveys or questionnaires
  • Attend clinic visits, tests or follow-up appointments
  • Use digital tools or wearable devices to monitor their health

Participants can ask questions at any stage and can choose to withdraw from a study at any time. The level of involvement varies between studies, and participants are encouraged to discuss any questions or concerns with the research team throughout the process.

The Importance of the Patient Voice

People living with heart disease bring valuable insights that help researchers design studies that are relevant, practical, and meaningful. When patients are involved in research, the outcomes are more likely to reflect the needs and priorities of the community they are intended to serve.